An increase in sedentary time from childhood is associated with a significant increase in blood insulin concentration, a new study shows. However, light physical activity could reduce the risk of excess insulin and insulin resistance. The study was conducted in collaboration between the Universities of Bristol and Exeter, and the University of Eastern Finland, and
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Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism. The loss-of-function mutation of KMT2C, a gene involved in histone modification, leads to the development of autism and other neurodevelopmental deficits. However, the precise mechanism of the disease progression is still unknown. Now, researchers from Japan have developed an animal model and elucidated
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The SUNRISE European Study Group, led by experts in physical activity and children’s health, is urgently appealing to countries across Europe to take specific measures to promote healthy movement behaviors in children aged under five years. Under the leadership of Jesús del Pozo, an expert in the Epidemiology of Physical Activity and (children’s) health and
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Researchers have discovered a blood protein that could help detect which children will experience ongoing concussion symptoms more than two weeks after an injury. The research, led by Murdoch Children’s Research Institute (MCRI) and published in the Journal of Neurotrauma, found the protein was a potential biomarker for delayed recovery from concussion in children. For
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In a recent review published in the journal Nutrients, researchers explored the role of maternal factors in preventing food allergies. Study: Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention. Image Credit: Pixel-Shot / Shutterstock Background Food allergies are a serious worldwide health problem, especially among youngsters, resulting in higher healthcare expenses. Common
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In a recent study published in the journal Nature Medicine, researchers evaluated associations between maternal diabetes mellitus (MDM) and the risk of attention-deficit/hyperactivity disorder (ADHD) in the offspring. Sixteen percent of pregnant individuals experience hyperglycemia worldwide. The prevalence of MDM has increased globally, which is associated with the advancing maternal age, the growing obesity epidemic,
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In a report published on March 21, 2024 in EMBO Molecular Medicine (A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion) investigators at Seattle Children’s Research Institute and Sanaria Inc. describe the development of a whole malaria parasite vaccine strain that infects the liver, develops to the late liver stage, and then
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A new study found that during the pandemic pediatric emergency departments (EDs) saw more children and adolescents who needed a psychiatric admission, as well as an increase in severe conditions, such as bipolar disorder, schizophrenia and substance use disorders. The higher demand for a psychiatric inpatient bed often exceeded availability, resulting in over 12-hour stays
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On March 27, 2024, Ann & Robert H. Lurie Children’s Hospital of Chicago treated its first patient with ELEVIDYS (delandistrogene moxeparvovec-rokl), the first gene therapy for Duchenne muscular dystrophy – a rare, genetic disease characterized by progressive muscle damage and weakness. Lurie Children’s is the first in Illinois to administer this treatment after ELEVIDYS received
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A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington’s disease and multiple cancers. The UC Irvine Tandem Genome Aggregation Database enables researchers to
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Sponsored Content by TecanApr 8 2024 Thought LeadersDr. Church Molecular and Pediatric PathologistBoston Children’s Hospital In this interview, Dr. Church, the Molecular and Pediatric Pathologist at Boston Children’s Hospital, talks to NewsMedical about their work in pediatric oncology, and the need to expand research and clinical options for children with cancer. What inspired you to focus
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Researchers with McMaster University have crafted the first-ever guidelines to help prepare families who plan to build their child’s tolerance to common food allergens. These international guidelines, published on April 8, 2024 in the Journal of Allergy and Clinical Immunology, standardize the preparation process for families considering oral immunotherapy, a process that involves giving very
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